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Tazobactam acid
CAS No. 89786-04-9
Tazobactam acid( CL-298741 | YTR 830H )
Catalog No. M16459 CAS No. 89786-04-9
Tazobactam is a antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 30 | In Stock |
|
| 100MG | 39 | In Stock |
|
| 200MG | 52 | In Stock |
|
| 500MG | 71 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTazobactam acid
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NoteResearch use only, not for human use.
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Brief DescriptionTazobactam is a antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases.
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DescriptionTazobactam is a antibacterial penicillin derivative which inhibits the action of bacterial beta-lactamases.(In Vitro):Tazobactam (CL-298741) (5 μg/mL; 18 hours) has bactericidal activity and inhibit the growth of the bacteria in a dose-dependent manner.Tazobactam (CL-298741) (1-10 μg/mL; 6 hours; Prot. vulgaris and M. morgan) inhibits various types β-lactamase activity and with ID50 values of ＜ 10 μg/mL, respectively.(In Vivo):Tazobactam (CL-298741) (1000 mg/kg; i.p.; four times a day, for 36 and 84 hours; BALB/c mice) decreases the number of bacteria in mice and survived in low doses.
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In VitroTazobactam (CL-298741) (5 μg/mL; 18 hours) has bactericidal activity and inhibit the growth of the bacteria in a dose-dependent manner.Tazobactam (CL-298741) (1-10 μg/mL; 6 hours; Prot. vulgaris and M. morgan) inhibitsvarious types β-lactamase activity and with ID50 values of ＜ 10 μg/mL, respectively.
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In VivoTazobactam (CL-298741) (1000 mg/kg; i.p.; four times a day, for 36 and 84 hours; BALB/c mice) decreases the number of bacteria in mice and survived in low doses. Animal Model:BALB/c mice Dosage:1000 mg/kg Administration:Intraperitoneal injection; four times a day, for 36 and 84 hours Result:Decraesed the number of bacteria and neutrophils in BALF than in the control group.
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SynonymsCL-298741 | YTR 830H
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PathwayMicrobiology/Virology
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TargetAntibiotic
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Recptorβ-Lactamase
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number89786-04-9
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Formula Weight300.29
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Molecular FormulaC10H12N4O5S
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESC[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Overington JP, et al. Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
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